
The fourth season of the American television medical drama Grey's Anatomy, commenced airing in the United States on September 27, 2007 and concluded on May 22, 2008. The season continues the story of a group of surgeons and their mentors in the fictional Seattle Grace Hospital, describing their professional lives and the way they affect the personal background of each character. Season four had twelve series regulars with ten of them returning from the previous season, out of which eight are part of the original cast from the first season. The season aired in the Thursday night timeslot at 9:00 EST. In addition to the regular seventeen episodes, a clip-show narrated by the editors of People recapped previous events of the show and made the transition from Grey's Anatomy to Private Practice, a spin-off focusing of Dr. Addison Montgomery and aired on September 19, 2007, before the season premiere. The season was officially released on DVD as a five-disc boxset under the title of Grey's Anatomy: Season Four – Expanded on September 9, 2008 by Buena Vista Home Entertainment. For the first time in the show's history, many cast changes occur, seeing the first departure of two main cast members. The season received mixed response from critics and fans, resulting in several awards and nominations for the cast members and the production team. Show creator Shonda Rhimes heavily contributed to the production of the season, writing five out of the seventeen episodes. The highest-rated episode was the season premiere, which was watched by 20.93 million viewers. The season was interrupted by the 2007–2008 Writers Guild of America strike, which resulted in the production of only seventeen episodes, instead of twenty-three originally planned.
Name | Grey's Anatomy Season 4 |
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Air Date | September 27th, 2007 |
Genre | Drama |
Network | ABC |
Production Companies | The Mark Gordon Company, ShondaLand, ABC Studios, Touchstone Television |
Number of Episodes | 17 Episodes |
Plot Keywords | seattle, trauma, workplace, hospital, doctor, medical student, surgical interns, medical drama |











Episodes List
Grey's Anatomy Season 4 Episode 1 : A Change Is Gonna Come
September 27th, 2007Entering their first year as residents, Meredith Grey, Cristina Yang, Izzie Stevens and Alex Karev now have interns of their own to mentor. Among the ...
Grey's Anatomy Season 4 Episode 2 : Love/Addiction
October 4th, 2007A patient is in the hospital because they fell asleep in a hazardous situation. A patient's home laboratory blew up in an apartment building and the v...
Grey's Anatomy Season 4 Episode 3 : Let the Truth Sting
October 11th, 2007The doctors meet the world's oldest intern. Marcy brings in her son Henry because she finds his change in behavior suspicious. A patient named Connie ...
Grey's Anatomy Season 4 Episode 4 : The Heart of the Matter
October 18th, 2007A face familiar to one of the year-twos shows up and dredges up issues that were never really dealt with. A teen soccer player needs counseling becaus...
Grey's Anatomy Season 4 Episode 5 : Haunt You Every Day
October 25th, 2007It's Halloween at Seattle Grace! There may be jokes, pranks, and/or scare tactics. Some of the women form a club based on an experience they all share...
Grey's Anatomy Season 4 Episode 6 : Kung Fu Fighting
November 1st, 2007A patient comes to the ER with a dream and a condition which may prevent him form realizing it. Two patients are competing to win something big. One o...
Grey's Anatomy Season 4 Episode 7 : Physical Attraction, Chemical Reaction
November 8th, 2007Izzie and George's new-founded relationship results in them having bad sex. Callie's Chief Resident position is taken away from her, and Bailey is the...
Grey's Anatomy Season 4 Episode 8 : Forever Young
November 15th, 2007There has been a bus crash and the patients are in the ER. Meredith and Derek's relationship gets more complicated when he dates a fellow doctor. Mere...
Grey's Anatomy Season 4 Episode 9 : Crash Into Me (1)
November 22nd, 2007An ambulance crash endangers the lives of the paramedics involved, as Meredith and the Chief work on-site to save them, Bailey treats a patient who re...
Grey's Anatomy Season 4 Episode 10 : Crash Into Me (2)
December 6th, 2007Meredith works furiously to save a paramedic trapped in an ambulance; Lexie holds the life of a patient in her hands; Derek must rely on a nurse to sa...
Grey's Anatomy Season 4 Episode 11 : Lay Your Hands on Me
January 10th, 2008George has a surprise visitor. Bailey's family is falling apart. Derek sorts through what kissing Rose means. Meredith discovers something that doesn'...
Grey's Anatomy Season 4 Episode 12 : Where The Wild Things Are
April 24th, 2008Time has passed but not much has changed. Sexual angst still runs rampant in the halls of Seattle Grace. Derek and Rose have been dating and Meredith ...
Grey's Anatomy Season 4 Episode 13 : Piece of My Heart
May 1st, 2008Addison visits Seattle Grace because they need skills that only she has. Rebecca/Ava returns with news for Alex. Meredith and Derek's clinical trial e...
Grey's Anatomy Season 4 Episode 14 : The Becoming
May 8th, 2008The clinical trial continues to make progress. The anti-McSteamy club creates new initiatives but that isn't enough to stop one woman from spending ti...
Grey's Anatomy Season 4 Episode 15 : Losing My Mind
May 15th, 2008Dr. Wyatt refuses to let Meredith give up on therapy. Alex learns something else about Rebecca. The Chief wants Erica to perform a daring surgery. Chr...
Grey's Anatomy Season 4 Episode 16 : Freedom (1)
May 22nd, 2008A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someon...
Grey's Anatomy Season 4 Episode 17 : Freedom (2)
May 22nd, 2008A couple undergoes surgery. Derek and Meredith's clinical trial gets a second shot from a new patient. Izzie helps Alex. McSteamy hooks up with someon...